Topic: The Cell
Didactic Objectives: Discuss Cell and tissue characteristics, genetic and congenital disorders. Cellular Biology, fluid electrolyte and acid base imbalances.
· Cellular functions
· Cellular metabolism
· Cellular reproduction: The Cell Cycle
· Tissues
Genes and Genetic Diseases
· DNA, RNA, and Proteins: Heredity at the molecular level
· Chromosomes
· Elements of Formal genetics
· Transmission of genetic disease
· Linkage Analysis and gene mapping
· Multifactorial inheritance
Altered Cellular and Tissue Biology
· Cell adaptation
· Cell injury
· Manifestations of cell injury
· Cellular death
· Aging and altered Cellular and Tissue Biology
Altered Fluid, electrolyte, acid and Base Balances
· Distribution of body fluids
· Pediatric Considerations: Distribution of body fluids
· Geriatric considerations: Aging and distribution of Body fluids
· Alterations in Water movements
· Sodium, Chloride and water balance
· Alterations in sodium, water, and chloride balance
· Alterations in Potassium and other electrolytes
· Acid-base balance
Lab Activities:
Watch videos posted under course content.
Topic: Mechanisms of Self Defense
Didactic Objectives: Describe concepts of Immunity, Inflammation, wound healing, Infection, Stress and Disease.
Innate Immunity: Inflammation and Wound Healing
· Human defense mechanisms
· Innate immunity
· Acute and Chronic Inflammation
· Wound Healing
· Pediatric Considerations: Age-related Factors affecting innate immunity in the newborn child.
· Geriatric Considerations: Age-related factors affecting innate immunity in the elderly
Adaptive Immunity
· Third line of defense: Adaptive Immunity
· Antigens and immunogens
· Humoral immune response
· Cell mediated immunity
· Immune response: Collaboration of B cells and T cells
· Pediatric Considerations: Age-related factors affecting mechanisms of self-defense in the newborn child
· Geriatric considerations: Age-related factors affecting mechanisms of self-defense in the elderly
Infection and Defects in Mechanisms of Defense
· Infection
· Deficiencies in Immunity
· Hypersensitivity: Allergy, Autoimmunity, and Alloimmunity
Stress and Disease
· Historical background and general concepts
· Stress overview: Multiple mediators
· The stress response
· Stress, Personality, Coping, and Illness
· Geriatric Considerations: Aging and the stress-Age Syndrome
Lab Activities:
Watch videos posted under course content.
Topic: Cellular Proliferation: Cancer
Didactic Objectives:Discuss the biology, clinical manifestations, treatment, and epidemiology of cancer.
Biology, Clinical manifestations, and Treatment of Cancer
· Cancer terminology and Characteristics
· The Biology of cancer cells
· Cancer Invasion and Metastasis
· Clinical manifestations and Treatment
Cancer Epidemiology
· Genes, Environmental –Lifestyle factors, and risk factors
Cancer in Children
· Incidence and types of childhood cancer
· Etiology
· Prognosis
Lab activities:
Watch the videos posted under course content.
Topic: The Neurological System
Didactic Objectives: Discuss Pain, temperature, sleep, sensory function, Alterations in cognitive systems, cerebral hemodynamics, motor functions, disorders of the central and peripheral nervous systems and neuromuscular junction, and alterations of neurologic functions in children.
Pain, Temperature, sleep and sensory function
· Pain
· Temperature regulation
· Sleep
· The special senses
Geriatric considerations: Aging and changes in hearing
Geriatric considerations: Aging and changes in olfaction and taste
· Somatosensory function
Alterations in cognitive systems, cerebral hemodynamics, and motor functions
· Alterations in cognitive systems
· Alterations in cerebral hemodynamics
· Alterations in neuromotor function
· Alterations in complex motor performance
· Extrapyramidal syndromes
Disorders of the central and peripheral nervous systems and neuromuscular junction
· Central nervous system disorders
· Peripheral nervous system and neuromuscular junction disorders
· Tumors of the central nervous system
· Normal growth and development of the nervous system
· Structural malformations
· Encephalopathies
· Cerebrovascular disease in children
· Tumors
Lab activities:
Watch the videos posted under course content.
Topic: The Endocrine system
Didactic Objectives: Discuss Mechanisms of Hormonal regulation and alterations of Hormonal regulation
Mechanisms of hormonal regulation
· Mechanisms of hormonal regulation
· Structure and function of the endocrine glands
· Geriatric considerations: Aging and its effect on specific endocrine glands.
Alterations of hormonal regulation
· Mechanisms of hormonal alteration
· Alterations of the hypothalamic-pituitary system
· Alterations of thyroid function
· Alterations of parathyroid function
· Dysfunction of the endocrine pancreas
· Chronic complications of diabetes
· Alterations of adrenal function
Lab activities:
Watch the videos posted under course content.
Topic: The Hematologic System
Didactic Objectives: Discuss alterations of hematologic function and alterations of hematologic function in children.
Alterations of hematologic function
· Alterations of erythrocyte function
· Classification of anemias
· Myeloproliferative red cell disorders
· Alterations of leukocyte function
· Alterations of lymphoid function
· Alterations of splenic function
· Alterations of platelets and coagulation
Alteration of hematologic function in children
· Disorders of erythrocytes
· Disorders of coagulation and platelets
· Neoplastic disorders
Lab Activities:
Watch videos posted under course content.
Topic: The Cardiovascular and Lymphatic Systems
Didactic Objectives: Discuss alterations of cardiovascular function, and alterations of cardiovascular function in children.
Alterations of Cardiovascular Function
· Diseases of the veins
· Disease of the arteries
· Disorders of the heart wall
· Manifestations of heart disease
· Shock
Alterations of Cardiovascular function in Children
· Congenital heart defects
· Acquired Cardiovascular disorders
Lab activities:
Watch videos posted under course content.
Topic: Pulmonary Function
Didactic Objectives: Discuss Alterations of pulmonary function and alteration of pulmonary function in children.
Alterations of pulmonary function
· Clinical manifestations of pulmonary alterations
· Disorders of the chest wall and pleura
· Pulmonary disorders
· Geriatric considerations: Aging and the pulmonary system
Alterations of pulmonary function in children
· Disorders of the upper airway
· Disorders of the lower airway
· Sudden infant death syndrome
Lab activities:
Watch videos posted under course content.
Topic: The Renal Urologic System
Didactic Objectives: Discuss Alterations of renal and urinary tract function and alterations of renal and urinary tract function in children.
Alterations of Renal and urinary tract function
· Urinary tract obstruction
· Urinary tract infection
· Glomerular disorders
· Acute kidney injury
· Chronic kidney disease
· Pediatric considerations: Pediatrics and renal function
· Geriatric considerations: Aging and renal function
Alterations in Renal and Urinary tract function in children.
· Structural abnormalities
· Glomerular disorders
· Bladder disorders
· Nephroblastoma
· Urinary incontinence
Lab Activities:
Watch the videos posted under course content.
Topic: The Digestive System
Didactic Objectives: Discuss alterations of digestive function and alterations of digestive function in children.
Alterations of digestive function
· Disorders of the gastrointestinal tract
· Disorders of the accessory organs
· Cancer of the digestive tract
Alterations of digestive function in children
· Disorders of the gastrointestinal tract
· Disorders of the liver
Lab Activities:
Watch the videos posted under course content.
Topic: The Musculoskeletal System
Didactic Objectives: Discuss Alterations of musculoskeletal function and alterations of musculoskeletal function in children.
Alterations in musculoskeletal function
· Musculoskeletal injury
· Disorders of bone
· Disorders of joints
· Disorders of skeletal muscle
· Musculoskeletal trauma
· Aging and the musculoskeletal system
Alterations of musculoskeletal function in children
· Congenital defects
· Bone infection
· Juvenile idiopathic arthritis
· Osteochondrosis
· Scoliosis
· Muscular dystrophy
· Musculoskeletal trauma
· Musculoskeletal tumors
· Nonaccidental trauma
Lab Activities:
Watch the videos posted under course content.
Topic: Integumentary
Discuss: Structure, function, and disorder of the integumentary system in adults and children.
Structure, function, and disorders of the integument
· Structure and function of the skin
· Geriatric considerations: aging and changes in skin integrity
· Disorders of the skin
· Disorders of the hair
· Disorders of the nails
Alterations of the integument in children
· Acne vulgaris
· Dermatitis
· Infections of the skin
· Insect bites and parasites
· Hemangiomas and vascular malformations
· Other skin disorders
Lab Activities:
Watch the video posted under course content.